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Detailed Program (Poster)
Detailed Program
Code No. |
BM-P37 |
Name |
Prof. Byeong Hee Kim |
Affiliation |
Kangwon National University |
Title |
Anti-cell adhesion characteristics of nanotextured surface |
File of Abstract |
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Co-author-1 | Prefix | Mr. |
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Country | Korea |
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First name | Eui Don |
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Last name | Han |
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Affiliation | Kangwon national University |
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Department | Mechatronics engineering |
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E-mail | luvkhy@kangwon.ac.kr |
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Cell phone | 8210-2368-2614 |
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Co-author-2 | Prefix | Prof. |
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Country | Korea |
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First name | Young Ho |
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Last name | Seo |
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Affiliation | Kangwon National University |
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Department | Mechatronics engineering |
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E-mail | mems@kangwon.ac.kr |
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Cell phone | +82-10-6408-0430 |
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Contents |
Temporary implantable biomedical devices such as intramedullary nails and stent need to inhibit cell adhesion and proliferation in contrast with permanent implantable medical devices. Various studies were carried out for inhibition of endothelialization, however, most methods needed complicated processes and were not permanent. In this paper, a permanent anti-cell adhesion surface was presented using nanotexturing method of nano-imprinting process. Cell adhesion characteristics on nanotextured polymer layer was compared to that on the planar polymer surface and cell culture dish. NIH3T3 fibroblast cell was cultured each substrate and investigated. Fig 1. shows cultured cells after 56 hours on each substrate. Contrastively, cells on the nanotextured polymer surface couldn’t adhered actively compared to another substrates during the whole culture time. Fig 3. represents the ratio of fibroblast cell covered area to cultured area for each substrate according to cell culture time. Cell adhesion area of nanotextured surface was less than half of that in cell culture dish and planar polymer substrate. According to results, anti-cell adhesion characteristics could be permanently assigned through surface nanotexturing method without any chemical treatment. |
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